Three years ago I had a shoulder replacement surgery. Pain as expected during recovery and PT. Then I had full range of motion and NO pain for about two years. Earlier this year it started hurting and getting worse and worse monthly. Due to the metal, we couldn?t get good xray images but due to where it hurt we expected a Rotator Cuff tear. So I go to what was supposed to be a one or two hour surgery this past Tuesday, but woke up 6 hours later. The doctor took samples to pathology to make sure that I didn?t have an infection, and instead it showed that I had Giant white blood cells in the area. The white cells had prevented any new bone from growing around the implant, so eventually it started breaking up. My doctor feels this was likely caused by Sjogrens Syndrome (or some other Auto Immune disease) fighting the foreign object and not allowing new bone to grow. This time he used cadaver bone mixed with something else and made a few other changes. If this doesn?t work, I?ll have to have a reverse shoulder replacement which uses different muscles. Not fun! Two months in a sling with a pillow, then months of PT. For the next two months I can only bend over when standing and do pendulum swings. Have any of you heard of Sjogrens syndrome or other Autoimmune disease causing anything similar to this?